Name: Deubiquitylases: from mechanism to physiology
Start: 2019-06-17
End: 2019-06-19
Location: University of Edinburgh

18 July - 20 July

All of the day

The PI3K/PTEN pathway: from basic science to clinical translation

Organiser

Biochemical Society

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Location

Palace Hotel, Buxton, UK

Category

Biochemical Society Events

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This conference will focus on the biology and signalling of the class I isoforms of PI3K, their downstream targets such as Akt/PKB and the drugs that have been generated to interfere with their function in disease. The speaker programme will bring together researchers to bridge the gap between basic science and translation, as well as industry figures who will provide an update on their PI3K programmes, and clinicians to share their feedback from some of the clinical trials.

This exciting event aims to provide a forum to share the latest discoveries, expand on the understanding of the basic biology science and signalling and examine novel translational opportunities, including neuroprotection and the treatment of rare diseases driven by PI3K pathway deregulation.

16 July

All of the day

Practical Python: Resources for analysing biological data with Python

Organiser

Biochemical Society

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Location

University of York, UK

Category

Biochemical Society Events

Training Events & Courses

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This practical event will explore the use of modern Python and associated resources for analysing and exploring biological data in the big data world. This course will be ideal for any beginner/intermediate user of Python, with or without prior experience in other programming languages.

During this session, participants will focus on how best to solve problems using this resource. The course will cover data handling and manipulation using the Pandas library, visualisation with the Matplotlib/Pyplot library and machine learning and statistics with the Scikit-learn library. Live demonstrations will be given, as well as an open session for questions. By the end of the course, participants should be able to install a Python IDE, read data in many formats, and apply some visualisation and analysis techniques.

15 July - 17 July

All of the day

Protein engineering II: from new molecules to new processes

Organiser

Biochemical Society

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Location

University of York, York, UK

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Biochemical Society Events

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The ability to engineer proteins to tackle new challenges has had a transformational effect across the biological and physical sciences, in both industrial and academic settings. The rate at which new methods are being developed shows no sign of slowing. This timely meeting will cover recent developments in the engineering of proteins.

Themes include new methods such as computational design, high throughput screening, and genetic code expansion, targets such as new biotherapeutics, scaffolds and catalysts, and the applications to which these are being applied, including diagnostics and sensing, nanotechnology, and synthetic biology.

As such this will be an interdisciplinary meeting that will demonstrate the state-of-the-art of the field, and will bring together a diverse set of researchers, making this an ideal forum for the exchange of new ideas.

03 July - 05 July

All of the day

Translation UK 2019

Organiser

Biochemical Society

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Location

Strathclyde Business School, Glasgow, UK

Category

Biochemical Society Events

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This event has sold out. To be added to the waiting list please email
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Translation UK is an annual meeting for a research community interested in understanding the mechanisms and control of mRNA translation and its implications for development, disease, agriculture and biotechnology.

It aims to:

Provide a forum for UK and European scientists working in this field to meet, present their latest findings and exchange ideas and potentially establish new research collaborations.
Provide opportunities for junior researchers to present their work and engage with leaders in this research field.
Invite speakers to enhance the meeting program and the stature of the UK translation field.

Topics in this meeting may be invited to submit to our journal, Biochemical Society Transactions, or other publication published by Portland Press, the wholly-owned trading subsidiary of the Biochemical Society.

01 July - 03 July

All of the day

Redox Signalling in physiology, ageing and disease

Organiser

Joint Event

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Location

Copthorne Hotel, Newcastle-upon-Tyne, UK

Category

Biochemical Society Events

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A joint Biochemical Society and BSRA Scientific Conference

The goal of this meeting is to bring biochemists, cell and systems biologists investigating redox-signalling mechanisms in a variety of systems, together with those working on the biological mechanisms underlying ageing and age-associated diseases. As such this meeting with provide an interdisciplinary forum for discussion of new approaches to the study of redox regulation, the mechanisms involved, and the role of redox dysregulation in health, ageing and disease.

Topics will include:

Biological sources and metabolism of reactive oxygen species
Tools for measuring ROS, redox changes and elucidating redox-signalling mechanisms
Redox-regulated physiological processes and stress responses
Biochemistry of redox-signalling; thiol oxidation, redox-relays, redoxin systems and glutathione
The roles of ROS in ageing and disease

17 June - 19 June

All of the day

Deubiquitylases: from mechanism to physiology

20 May

All of the day

R for Biochemists 101

29 April

The Changing Landscape of Research on Ageing: Models, Mechanisms and Therapies

Organiser

Biochemical Society

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Location

Beatson Institute for Cancer Research

Glasgow, UK

Category

Biochemical Society Events

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A Biochemical Society Scientific Meeting

The number of aged individuals in the World’s population is growing. Improvements in health span have not matched the increase in the average human lifespan. Consequently, there is an urgent need to address the associated increase in age related morbidities and to understand and separate natural ageing processes from processes specific to morbidities, in order to improve health span.

This meeting will capture the cutting-edge of the field of Geroscience, covering a broad front of exciting research into aspects of mammalian ageing, from hallmarks including cellular senescence and nutritional and epigenetic dysregulation, through to progeric diseases, gerontogens and emerging therapies to address these. As ageing is a process, it is important to address the underpinning mechanisms and how these interplay over the life course and in the general population, to mitigate the impact of psychosocial and socioeconomic and environmental issues caused by a growing demographic of the aged in society.

This symposium will explore gaps in knowledge between the basic science and both its clinical and social translational applications. Critically, it will explore emerging environmental factors, including the microbiome, and how these interplay with the genome and epigenetic landscape of ageing. The symposium is designed to be suitable for basic scientists, clinical scientists, health professionals and industry.

View full programme here.

This event will also be live streamed for those unable to get to Glasgow. If you wish to attend online please select ‘live stream’ during registration.

As an online delegate you can watch a private live stream of the talks from the comfort of your office or home via a personalised link, ask questions to speakers and network with other remote delegates.

Topics in this meeting may be invited to submit to our journal, Biochemical Society Transactions, or other publication published by Portland Press, the wholly-owned trading subsidiary of the Biochemical Society.

Oral communication slots are available at this meeting.

All attendees, particularly researchers in the early stages of their career, are invited to submit a poster abstract for consideration as an oral communication.

Grants and Bursaries

The Biochemical Society offers a programme of grants and bursaries supporting research, attendance at scientific conferences and the sponsorship of events.

Not a member of the Biochemical Society? Join today and save up to £100 on your registration fee.

03 April - 05 April

All of the day

2nd UK Workshop on Membrane proteins: solubilisation and biophysical characterisation

19 March

All of the day

Practical Python: Resources for analysing biological data with Python

Organiser

Biochemical Society

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Location

Online

Category

Biochemical Society Events

Training Events & Courses

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This introductory course is aimed at biochemists, physiologists, pharmacologists and those working across more than one discipline. This practical half-day session will explore the use of modern Python and associated resources for analysing and exploring biological data in the big data world. This course will be ideal for any beginner/intermediate user of Python, with or without prior experience in other programming languages.

During this session, participants will focus on how best to solve problems using this resource. The course will cover data handling and manipulation using the Pandas library, visualisation with the Matplotlib/Pyplot library and machine learning and statistics with the Scikit-learn library. Live demonstrations will be given, as well as an open session for questions. By the end of the course, participants should be able to install a Python IDE, read data in many formats, and apply some visualisation and analysis techniques.

This half-day training workshop ran alongside the Life Sciences 2019: Post-translational modifications and cell signalling meeting.

17 March - 18 March

All of the day

Life Sciences 2019: Post-translational modification and cell signalling

10 December

2018 Industry and Academic Collaboration Award Lecture: Validating disease targets using open access chemical probes

Organiser

Biochemical Society

Location

Brighton and Sussex Medical School Teaching Building

Sussex University, UK

Category

Biochemical Society Events

The inaugural Industry and Academic Collaboration Award will be awarded in 2018 to Stefan Knapp from the Institute of Pharmaceutical Chemistry, the Buchmann Institute for Molecular Life Sciences at Frankfurt University as well as at the Structural Genomics Consortium at Oxford University.

His research team made a major contribution to the understanding of structural mechanisms regulating signalling molecules such as protein kinases, phosphatases, acetylation dependent reader domains of the bromodomain family and the exploitation of this knowledge for the development of highly specific inhibitors. In the framework of a large collaborative network involving many academic research groups and industry, he pioneered the development of protein interaction inhibitors targeting bromodomains that function as lysine acetylation dependent reader domains of the epigenetic code as well as highly specific allosteric inhibitors modulating kinase function.

The lecture, entitled ‘Validating disease targets using open access chemical probes’ will take place at the Brighton and Sussex Medical School Teaching Building, University of Sussex, UK.

Register to attend.

The lecture is free to attend and open to all.

Programme:

16:00-17:00 Award presentation and lecture: Validating disease targets using open access chemical probe

17:00-18:00 Drinks reception

22 November - 23 November

Young Life Scientists’ Symposium 2018 – Genome Integrity: a lifetime’s challenge

19 November - 20 November

Synthetic Biology UK 2018

Organiser

BrisSynBio

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Location

We the Curious

Bristol, UK

Category

Biochemical Society Events

Scientific Meetings

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A Joint Biochemical Society and BrisSynBio Scientific Meeting

SBUK is the premiere UK synthetic biology meeting, bringing together all flavours of synthetic biology to foster a cohesive, vibrant and multidisciplinary community that is inclusive, open to innovation, collaboration and supportive of young talent.

The University of Bristol hosts SBUK 2018, bringing a unique focus on synthetic biology approaches to biomolecular design and engineering.

The scientific programme showcased some of the very best of the UK and international synthetic biologists. Particular attention will be devoted to oral and poster presentations from early career scientists, with dedicated sessions for networking, and a vibrant social programme.

Some Topics in this meeting were invited to submit to our journal, Biochemical Society Transactions, or other publication published by Portland Press, the publishing arm of Biochemical Society.

16 November

Shaping Your Career in Molecular Biosciences: Taking a Wider View

Organiser

Biochemical Society

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Location

Technology and Innovation Centre

Glasgow, UK

Category

Biochemical Society Events

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This half-day event was open to anyone looking to progress their career in molecular bioscience.

Participants had the opportunity to attend sessions on a range of topics, including:

Marketing yourself to different audiences
Mapping your job applications based on the advert and criteria
Moving between academia and industry
What skills you can gain on an internship or placement

The event followed the Young Life Scientists’ Symposium (YLS) on Molecular Neuropharmacology in Health & Wellbeing on 15 November.

Grants and Bursaries

The Biochemical Society offers a programme of grants and bursaries supporting research, attendance at scientific conferences and the sponsorship of events.

Please note that there is was no abstract submission for this event.

29 October - 30 October

Key Aspects of Modern Drug Discovery

Organiser

Biochemical Society

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Location

Charles Darwin House

London, UK

Category

Biochemical Society Events

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This training event aimed to provide a comprehensive overview of the pre-clinical drug discovery process. Designed and delivered by experts from industry and academia, the event was suitable for recent graduates, PhD students and early career scientists interested in working in the pre-clinical drug discovery industry.

The course focused on small molecule target identification and validation, hit-to-lead and lead optimisation, as well as on pre-clinical drug development and toxicology. ‘Key aspects of modern drug discovery’ comprised lectures, case studies, group discussions and a drinks reception to encourage networking and collaboration among delegates and speakers.

Speakers included:

Rick Davies, AstraZeneca
Jacqui Piner, GSK
John Unitt, Sygnature Discovery
Heather Wallace, University of Aberdeen
Rupert Satchell, Sygnature Discovery
Andy Davis, AstraZeneca
John Ladbury, University of Leeds

The event was developed in collaboration with the Royal Society of Chemistry, and supported by the Royal Society of Biology and the British Pharmacological Society.

10 September - 12 September

Acylation of intracellular and secreted proteins: mechanisms and functional outcomes

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Location

Old Ship Hotel

Brighton, UK

Category

Biochemical Society Events

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A Biochemical Society Scientific Meeting

Programme Co-ordinators:

Luke Chamberlain (University of Strathclyde, UK)

Tony Magee (Imperial College, UK)

Protein acylation events are crucial lipidation processes playing a fundamental role in cell physiology. Recently there has been a surge of interest in two acylation pathways: S-acylation, the modification of intracellular proteins by fatty acids attached to cysteine, and the acylation of secreted proteins including Ghrelin, Wnts and Hedgehogs. Although these two acylations occur on different sides of cell membranes and are catalysed by different enzyme families (zDHHC and MBOAT respectively), research into each pathway informs the other. These acylation pathways have seen important advances over recent years that make this meeting particularly timely, including: new insight into the enzymology and regulatory effects of these lipid modifications; seminal 3D structures of acylating enzymes; development of novel chemical biology-based methodologies that have supported new breakthroughs; and the identification of links between acylation and disease and the potential for pharmaceutical intervention.

The aims of the meeting are to provide a forum for the discussion of new discoveries in the field of protein acylation and to accelerate new discoveries by supporting the development of new collaborations and exchange of ideas and technical expertise. The specific learning objectives are:

To highlight the structure and function of enzymes that catalyse S-acylation and the acylation of soluble secreted proteins
To understand how the attachment of fatty acids onto proteins impacts their trafficking and function
To dissect how cell physiology and intracellular signalling is regulated by protein acylation
To understand how acylation enzymes can be targeted as a therapeutic strategy in a variety of disorders
To exemplify how new chemical biology approaches and other technological developments can be used to advance discovery in the protein acylation field

Topics in this meeting may be invited to submit to our journal, Biochemical Society Transactions, or other publication published by Portland Press, the wholly-owned trading subsidiary of the Biochemical Society.

Oral communication slots are available at this meeting.

All attendees, particularly researchers in the early stages of their career, are invited to submit a poster abstract for consideration as an oral communication.

Student Bursaries are available for this meeting.

Not a member of the Biochemical Society? Join today and save up to £100 on your registration fee.

10 September

All of the day

R for Biochemists 101 2018

09 September - 12 September

84th Harden Conference: Single-molecule bacteriology

Organiser

Biochemical Society

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Location

Lady Margaret Hall

Oxford, UK

Category

Biochemical Society Events

Harden Conference

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Single-molecule imaging has revolutionised our ability to study molecular processes underlying bacterial cell function. Using single fluorescent molecules to break the optical microscopy limit (~200 nm), we can achieve resolutions of ~20 nm in living cells, a scale previously accessible only by electron microscopy. New fluorescent proteins and dyes, ultrasensitive microscopy, and image-analysis software have also helped us visualise reactions, interactions and motions inside single bacteria; we can follow single protein machines as they function, and observe fine cellular structures transforming during the cell cycle. In a sense, we are “re-discovering” bacteria with a new set of eyes.

This toolbox is ideal for quantitative biology; we can count molecules, and monitor their intracellular location, mobility and kinetics inside cell populations. Combined with powerful modelling, imaging transforms our understanding of bacteria as complex systems and synthetic-biology vectors.

With this interdisciplinary meeting, we will showcase the most exciting developments in this young field to a UK and European audience. In selecting speakers, we aimed at scientists using cutting-edge single-molecule imaging to study mechanisms inside single cells. We also aspired to connect world-leading physicists/engineers driving rapid progress in methods with microbiologists applying advanced imaging to long-standing questions in bacteriology. Overall, the meeting will help build a multidisciplinary community working on key mechanisms of bacteria life.

The meeting will cover structural/mechanistic studies of processes using super-resolution imaging and single-molecule methods (tracking, bleaching, co-localisation, FRET). Many processes involve nucleic acids (chromosome organization, DNA replication, repair, recombination, and segregation, gene expression, CRISPR mechanisms), whereas others relate to signal transduction, cell division, cell-wall biosynthesis, and motility. The meeting will also explore new quantitative in vivo techniques applicable to bacteria: theoretical approaches (modelling stochastic gene expression), microfluidics, site-specific labelling, cytological profiling, high-throughput approaches). A third theme will involve studies of clinical/commercial significance (biofilms, pathogenic bacteria, bacterial persistence, antibiotic resistance).

Programme coordinators

Achillefs Kapanidis, University of Oxford, UK
Meriem El Karoui, University of Edinburgh, UK
Stephan Uphoff, University of Oxford, UK
Jie Xiao, John Hopkins University, USA

Unique to the Biochemical Society, Harden Conferences are residential research conferences covering a specialist topic.

The conferences bring together scientists from various backgrounds with a common interest in – but varying approaches to – the topic of the conference.

To maintain a suitably high level of discussion and presentation at the conference, it is desirable that participants be experienced in the field covered; most of the participants will be expected to have postdoctoral or equivalent experience, although Ph.D. students will also be welcome.

View full programme here.

The planned scientific sessions feature speakers invited by the Organizers and, in addition, time is left for extensive discussion and for short contributions, including posters, by other conference participants.

Harden Bursaries

We offer a limited number of bursaries to assist younger members of the Biochemical Society to attend the conferences.

02 September - 04 September

Biennial International LRRK2 Meeting

Organiser

Biochemical Society

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Location

The Botanical Garden

Padua, Italy

Category

Biochemical Society Events

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A Biochemical Society Scientific Meeting

Leucine Rich Repeat Kinase 2 has emerged as a major genetic determinant of Parkinson’s disease, placing this multidomain enzyme at the core of research efforts for the development of both disease modifying therapies as well as disease related biomarkers. Given the success of the previous LRRK2 focused meetings, we launch a third edition of this event where the latest biochemical, cellular and translational LRRK2 research will be discussed in the frame of future clinical applications.

Topics include:

LRRK2 genetics
LRRK2 structural biology
LRRK2 animal models
LRRK2 in immune function
LRRK2 intracellular pathways
LRRK2/alpha-synuclein interaction in Parkinson’s disease pathogenesis
LRRK2 in neuronal function
LRRK2 substrate and effectors
LRRK2 pathways to clinic
LRRK2 in other diseases

View full programme here.

Abstract deadline: Abstract submission has now closed.

Oral communication slots are available at this meeting. All attendees, particularly researchers in the early stages of their career, are invited to submit a poster abstract for consideration as an oral communication.

Student Bursaries are available for this meeting.

Not a member of the Biochemical Society? Join today and save up to £100 on your registration fee.

02 August - 03 August

Structure and Mechanisms of Membrane Proteins

Organiser

Biochemical Society

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Location

Maple House

Birmingham, UK

Category

Biochemical Society Events

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A Biochemical Society Scientific Meeting

Registration is now closed.

This timely two-day meeting will bring together membrane protein structural biology experts to present their recent work on membrane proteins involved in different aspects of human health, disease and cellular functions. The talks will cover the structure and mechanism of membrane protein transporters, channels and G protein-coupled receptors (GPCRs). The meeting will bring together experts from both academia and industry to foster colalborative efforts.

View the full programme here.

Oral communication slots are available at this meeting. All attendees, particularly researchers in the early stages of their career, are invited to submit a poster abstract for consideration as an oral communication.

Grants and Bursaries

The Biochemical Society offers a programme of grants and bursaries supporting research, attendance at scientific conferences and the sponsorship of events.

Not a member of the Biochemical Society? Join today and save up to £100 on your registration fee.

Publishing

Topics in this meeting may be invited to submit to our journal, Biochemical Society Transactions, or other publication published by Portland Press, the wholly-owned trading subsidiary of the Biochemical Society.

31 July - 01 August

Experimental Techniques for Studying Proteins and Lipids in Biological Membranes

09 July - 11 July

Proteomics and Related Metabolomics of Oxidative Damage and Glycation: A Technical Workshop

Organiser

Biochemical Society

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Location

University of Warwick

Coventry, UK

Category

Training Events & Courses

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Biochemical Society Training Event

*Multiple booking discounts are available for this meeting. Register 5 delegates and fifth delegate can attend free of charge. (Free place will be given to the lowest cost registration only) Contact the Conference Office for more details.*

This three-day training event will focus on the practical aspects of proteomics and metabolomics of oxidative damage and glycation. The course will provide an introduction to mass spectrometry for biochemists, biologists and biomedical scientists from PhD level and above. Participants are not expected to have prior knowledge of mass spectrometry, but a keen interest in protein damage and metabolites. The event will comprise lectures and hands-on laboratory sessions.

The course aims to equip participants with the practical skills required for the design and the successful implementation of experiments in proteomics and metabolomics of oxidative damage and glycation. Participants will practice different methods of sample preparation, including simple to complex mixtures and enrichment techniques. Demonstration samples will be run on our cutting-edge instrumentation and, as a delegate, you will have the opportunity to explore custom method design for your particular requirements. The course will then focus on data analysis to address protein identification, modifications and quantification.

Grants and Bursaries

The Biochemical Society offers a programme of grants and bursaries supporting research, attendance at scientific conferences and the sponsorship of events.

09 July - 12 July

Small G proteins in cellular signalling and disease

Organiser

Biochemical Society

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Location

Clare College

Cambridge, UK

Category

Biochemical Society Events

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A Biochemical Society Scientific Meeting

Register to live stream the conference

Small G proteins regulate a plethora of cell signalling pathways thus impacting on most biological processes. As a result of their broad spread cellular influence, the deregulation of these proteins and their pathways often results in disease, especially cancer. The interest, both academic and commercial, in these proteins has always been intense, but with the instigation of the Ras Initiative by the NCI in 2013, interest is newly invigorated. Hopes are high that new ways being developed will successfully target cancers driven by mutant Ras.

Topics in this meeting may be invited to submit to our journal, Biochemical Society Transactions, or other publication published by Portland Press, the wholly-owned trading subsidiary of the Biochemical Society.

Oral communication slots are available at this meeting. All attendees, particularly researchers in the early stages of their career, are invited to submit a poster abstract for consideration as an oral communication.

View full programme here.

Grants and Bursaries

The Biochemical Society offers a programme of grants and bursaries supporting research, attendance at scientific conferences and the sponsorship of events.

Not a member of the Biochemical Society? Join today and save up to £100 on your registration fee.

04 June - 06 June

All of the day

The Biology and Physics of Bacterial Chromosome Organisation 2018

Organiser

Biochemical Society

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Location

Golden Tulip

Leiden, The Netherlands

Category

Biochemical Society Events

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A Biochemical Society Scientific Meeting

Abstract Submission open for POSTERS ONLY: 4 May

In the recent years, collaborations between biologists and physicists have generated key discoveries regarding our understanding of bacterial chromosome structure. This conference will recognize the role of inter-disciplinary work and foster new collaborations and ideas.

New approaches and technologies have revolutionized the field of bacterial chromosome biology in the last fifteen years. For example, super-resolution microscopy is now being used to visualize previously unresolved structure, genomic tools have enabled the capture of new types of proximity information on a genomic-scale and polymer physics models allow researchers to tackle questions that go far beyond the traditional biological description of chromosome structure.

View programme.

The Biochemical Society is pleased to offer the Members registration fee to members of the Netherlands Society for Biochemistry and Molecular Biology (NVBMB:https://nvbmb.kncv.nl) for this meeting.

Topics in this meeting may be invited to submit to our journal, Biochemical Society Transactions, or other publication published by Portland Press, the wholly-owned trading subsidiary of the Biochemical Society.

Oral communication slots are available at this meeting. All attendees, particularly researchers in the early stages of their career, are invited to submit a poster abstract for consideration as an oral communication.

Grants and Bursaries

The Biochemical Society offers a programme of grants and bursaries supporting research, attendance at scientific conferences and the sponsorship of events.

Not a member of the Biochemical Society? Join today and save up to £100 on your registration fee.

03 June - 07 June

83rd Harden Conference: Autophagy – from Molecules to Disease II

Organiser

Biochemical Society

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Location

Chesford Grange

Warwickshire, UK

Category

Biochemical Society Events

Harden Conference

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Autophagy continues to be one of the most exciting and topical subjects in biology. Since the first Autophagy Harden Conference (the 68th Harden, held in 2010), our understanding of the basic regulatory mechanisms and the physiological roles of autophagy in health and disease has advanced substantially.

Recent years have seen an impressive diversification in autophagy techniques and model systems, as well as seeing autophagy knowledge put to many novel practical applications, including disease intervention for which novel autophagy modulators are in the pipeline. This meeting brings together experts in the autophagy field from across the world to present cutting edge research on the molecular control of autophagy and the roles of autophagy in immunity, physiology and disease.

View programme.

Oral communication slots are available at this meeting.

All attendees, particularly researchers in the early stages of their career, are invited to submit a poster abstract for consideration as an oral communication.

Unique to the Biochemical Society, Harden Conferences are residential research conferences covering a specialist topic.

The conferences bring together scientists from various backgrounds with a common interest in – but varying approaches to – the topic of the conference.

COST Members

A limited number of TransAutophagy Cost members are eligible to attend on a subsidized basis.

Priority will be given to early career investigators (ECIs) and members from ITC.

Please contact Jon Lane (Jon.Lane@bristol.ac.uk) or Sharon Tooze (Sharon.Tooze@crick.ac.uk) with a statement of interest and CV before the end of March if you are interested in attending.

Harden Bursaries

A limited number of bursaries are available to assist younger members of the Biochemical Society to attend the conferences.

Preference will be given to senior graduate students (or those who gained their Ph.D. in the last 5 years) and restricted to members of the Biochemical Society.

Not a member of the Biochemical Society? Join today and save up to £100 on your registration fee.

19 April - 20 April

30th Annual UK RNA Polymerase focused meeting

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Location

Charles Darwin House

London, UK

Category

Biochemical Society Events

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A Biochemical Society Scientific Meeting

There are many of active research groups in the UK working with RNA polymerases. The 30th Annual Meeting will provide a networking and collaborative opportunity for researchers, and provide a platform for early-career researchers to present their latest lab research.

With an aim to strengthen UK activity in the field, this ‘workshop’ style meeting gives it the unique position of being the only meeting in the UK dedicated to this topic

Abstract deadline: Closed

Earlybird registration deadline: 15 February 2018

Registration is now closed

Oral communication slots are available at this meeting

All attendees, particularly researchers in the early stages of their career, are invited to submit a poster abstract for consideration as an oral communication.

Grants and Bursaries

The Biochemical Society offers a programme of grants and bursaries supporting research, attendance at scientific conferences and the sponsorship of events.

Member’s Discount

Not a member of the Biochemical Society? Join today and save up to £100 on your registration fee.

17 April - 20 April

New Horizons in ESCRT Biology

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Location

Royal Holloway

University of London, UK

Category

Biochemical Society Events

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A Biochemical Society Scientific Meeting

The Endosomal Sorting Complex Required for Transport (ESCRT) machinery is an essential membrane-remodelling complex that is conserved throughout evolution as far back as archaea. Since their discovery in 2001 as regulators of cargo sorting to the yeast vacuole, work on the ESCRT machinery has exploded as our understanding of this machinery’s role in remodelling different membranes has grown.

In addition to their classical role in endosomal sorting, this machinery is co-opted to perform similar membrane-remodelling events allowing HIV-1 release, release of exosomes and microvesicles, membrane abscission during cytokinesis, neuronal pruning, repair of damaged regions of plasma membrane and regeneration and repair of the nuclear envelope.

Given the explosion of ESCRT-biology, many researchers are new to the field and will benefit from this meeting’s speakers, who comprise some of the leading active researchers who have been part of the wealth of exciting new discoveries in ESCRT research in recent years.

Topics covered include:

ESCRTs in cell division – cytokinesis and nuclear envelope remodelling
Viral exploitation of the ESCRT-machinery
Biochemical assembly of ESCRTs
Cargo sorting to the MVB
Membrane Trafficking
Emerging ESCRT functions

View programme.

Topics covered in this meeting may be invited to submit to our journal, Biochemical Society Transactions, or other publication published by Portland Press, the wholly-owned trading subsidiary of the Biochemical Society.

12 April - 13 April

Evolving Molecular Bioscience Education

Organiser

Biochemical Society

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Location

University of Chester

UK

Category

Biochemical Society Events

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A Biochemical Society and FEBS Training Event

This two-day training event is aimed at anyone teaching or supporting teaching in Higher Education, from early career researchers to established professors. The aim of the course is to share best practice and novel ideas with bioscience HE educators, to equip students with the key skills needed to succeed in their careers and enhance their experience. The event will comprise lectures, hands-on sessions, group discussions and poster presentations.

Topics include:

Evaluating teaching practice through pedagogical research
Engaging students in undergraduate research projects
Teaching and assessing large cohorts using interactive and engaging methods
Teaching postgraduate and international students

03 April - 04 April

BMP Signalling in Cancer II

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Location

St Anne's College

Oxford, UK

Category

Biochemical Society Events

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A Biochemical Society Scientific Meeting

Abstract deadline: closed

Registration: closed

Earlybird registration deadline: 31 January 2018

BMPs (body morphogenetic proteins) are members of the TGF-β family, which bind to and activate multiple receptor serine/threonine kinases. The BMP pathway regulates tissue development and regeneration. It has become clear that BMP signalling can be co-opted for both tumour initiation and promotion. These effects are strongly related to its role in regulating stem cells. Like TGF-β, BMP signalling can act as a tumour suppressor or tumour promoter, dependent on the microenvironmental context. For example, overexpression of the antagonist, Gremlin1 can promote colorectal cancer, while activating mutations in the BMP receptor kinase ALK2 drive a fatal paediatric glioma.

The aim of this conference is to explore the mechanisms of BMP signal transduction and to discuss how genetic and epigenetic alterations result in aberrant signalling and how this leads to cancer. Microenvironmental control of cancer cell function is a research area of intense interest and as a key mesenchymal-epithelial signalling pathway, BMP signalling is emerging as a key therapeutic target. We aim to discuss in detail how to manipulate the pathway, both positively and negatively with small molecules or biologics.

Topics in this meeting may be invited to submit to our journal, Biochemical Society Transactions, or other publications published by Portland Press, the wholly-owned trading subsidiary of the Biochemical Society.

The deadline for Oral communication abstracts is now closed for this meeting. All attendees, particularly researchers in the early stages of their career, are invited to submit a poster abstract for consideration.

Student Bursaries are available for this meeting.

Not a member of the Biochemical Society? Join today and save up to £100 on your registration fee.

01 April

All of the day

2018 Industry and Academic Collaboration Award Lecture: Validating disease targets using open access chemical probes

Location

Nottingham

UK

Category

Biochemical Society Events

Date: 10 December 2018

Brighton and Sussex Medical School Teaching Building, University of Sussex, UK

The inaugural Industry and Academic Collaboration Award will be awarded in 2018 to Stefan Knapp from the Institute of Pharmaceutical Chemistry, the Buchmann Institute for Molecular Life Sciences at Frankfurt University as well as at the Structural Genomics Consortium at Oxford University.

His research team made a major contribution to the understanding of structural mechanisms regulating signalling molecules such as protein kinases, phosphatases, acetylation dependent reader domains of the bromodomain family and the exploitation of this knowledge for the development of highly specific inhibitors. In the framework of a large collaborative network involving many academic research groups and industry, he pioneered the development of protein interaction inhibitors targeting bromodomains that function as lysine acetylation dependent reader domains of the epigenetic code as well as highly specific allosteric inhibitors modulating kinase function.

The lecture, entitled ‘Validating disease targets using open access chemical probes’ will take place at the Brighton and Sussex Medical School Teaching Building, University of Sussex, UK.

Programme:

16:00-17:00: Award presentation and lecture

16:00-17:00: Validating disease targets using open access chemical probe

17:00-18:00: Drinks reception

19 March - 21 March

The Dynamic Cell III

More Information

Location

Manchester Conference Centre

Manchester, UK

Category

Biochemical Society Events

More Info

More Information

A Joint Biochemical Society and BSCB Scientific Meeting

The Dynamic Cell III will provide a showcase for the latest cell biological research exemplifying the use of dynamic methods to interrogate cellular function and to explore mechanisms of cell motility and cell – cell interactions.

If you are unable to travel to Manchester we are delighted to be offering remote conference places at this meeting.

Watch a private live stream of the talks from the comfort of your office or home via a personalised link, ask questions to speakers and network with other remote delegates.

Topics

Cytoskeletal regualtion of cell division
Cell migration and the extracellular matrix
Cytoskeletal dynamics
Cell – cell interactions
Imaging and probing cell function

Oral communication slots are available at this meeting. All attendees, particularly researchers in the early stages of their career, are invited to submit a poster abstract for consideration as an oral communication.

Grants and Bursaries

The Biochemical Society offers a programme of grants and bursaries supporting research, attendance at scientific conferences and the sponsorship of events.

Not a member of the Biochemical Society? Join today and save up to £100 on your registration fee.

13 December

10:00 am - 5:30 pm

Capture Hi-C: Practical approaches to mapping genome-wide regulatory interactions

11 December - 13 December

8:00 am - 6:00 pm

New Approaches for Investigating Nascent Peptide Folding

27 November - 28 November

All of the day

Synthetic Biology UK 2017

10 November

All of the day

Hydrogen Bonds & DNA: Commemoration of the 70th anniversary of the discovery by JM Creeth and colleagues at Nottingham in 1947

23 October - 31 October

All of the day

R for Biochemists 101 2017

06 September - 08 August

All of the day

Insulin and exercise signalling for glucose homeostasis and metabolic health

04 September - 05 September

All of the day

Glycobiology in Infectious Disease

22 August - 25 August

All of the day

13:30 – 14:00	(S001) Silent polymorphic mutations (sSNP) speak out: alterations of protein function and folding by sSNPs Zoya Ignatova – Universitat Hamburg, Germany
14:00 – 14:30	Translation Rate and Protein Fate Patricia Clark – University of Notre Dame, USA
14:30 – 14:50	(OC006) The ribosome restrains molten globule formation in stalled nascent flavodoxin Carlo van Mierlo – Laboratory of Biochemistry; Wageningen University, Netherlands
14:50 – 15:10	(OC004) Kinetic and structural comparison of the co-translational and refolding pathways of HaloTag Avi Samelson – University of California, San Francisco, United States

15:40 – 16:10	(S002) Co-translational folding of alpha helical membrane proteins in lipid bilayers Paula Booth – Kings College London, UK
16:10 – 16:30	(OC002) Disulfide formation during nascent polypeptide folding Philip Robinson – University of Glasgow, United Kingdom

	(P001) The Endoplasmic Reticulum Membrane Protein Complex (EMC) cooperates with the Sec61 translocon to enable the biogenesis of polytopic membrane proteins Matthew Shurtleff – University of California, San Francisco
	(P003) Isolation of RNCs as a strategy to characterise ribosomal heterogeneity in M. tuberculosis Beth Sawyer – London School of Hygiene & Tropical Medicine, United Kingdom
	(P005) Translational Termination Factors catalyse the Release of the Nascent Chain on a Proline Codon in the 2A- coding mRNA Man Balola – Mosul University, United Kingdom
	(P007) The ribosome modulates cotranslational folding depending on protein size and net charge Jose Arcadio Farias Rico – Stockholm University, Sweden
	(P009) NMR measurements of dynamics and protein-ribosome interactions in ribosome–nascent chain complexes Christopher Waudby – University College London, United Kingdom
	(P011) The mechanism of cotranslational recognition of nascent substrate proteins by the translocation ATPase SecA Damon Huber – University of Birmingham, United Kingdom
	(P013) Assembly in the translation milieu imposes evolutionary constraints on homomeric proteins Eviatar Natan – The Aleph Lab
	(P015) Insights into Ribosome Force Profile Assays: Releasing the Stall Carolina Mendonca – University of Cambridge, United Kingdom

09:30 – 10:00	(S003) Structural and mechanistic insight into nascent-polypeptide mediated translational stalling Daniel Wilson – University of Hamburg, Germany
10:00 – 10:30	Structures of Prokaryotic and Eukaryotic Ribosomal Complexes Involved in Initiation, Maturation and Targeting of Proteins to Membranes Nenad Ban – ETH Zurich, Switzerland
10:30 – 10:50	(OC005) Origins of the Mechanochemical Coupling of Peptide Bond Formation and Protein Synthesis Edward O’Brien – Penn State University, USA

11:30 – 12:00	(S004) Cotranslational protein folding Gunnar von Heijne – Stockholm University, Sweden
12:00 – 12:30	Principles of Protein Structural Ensemble Determination Michele Vendruscolo – University of Cambridge, UK
12:30 – 13:00	Kinetics of peptide and protein aggregation Alexander Buell – University of Düsseldorf, Germany

14:00 – 14:30	(S005) Regulation of Human Translation Termination by Factors bound to the mRNA 3’Untranslated Region Christiane Berger-Schaffitzel – University of Bristol, United Kingdom
14:30 – 15:00	(S006) Structural studies of protein folding on the ribosome Lisa Cabrita – University College London, United Kingdom
15:00 – 15:20	(OC001) The translating human mitochondrial ribosome in action – snapshots observed by cryo-EM Shintaro Aibara – Science for Life Laboratory / Stockholm University, Sweden

	(P002) Investigating the insertion and folding of alpha helical membrane proteins into lipid bilayers using a cell free expression system Nicola Harris – King’s College London, United Kingdom
	(P004) Elongation Nascent Peptides in All-Atom Molecular Dynamics Simulations Michal H. Kolar – Max Planck Institute for Biophysical Chemistry, Germany
	(P006) Developing cell-free expression for studies of co-translational membrane protein folding Grant Pellowe – King’s College London, United Kingdom
	(P008) A component of the ribosome exit tunnel is required for Hox gene translation during Drosophila embryonic patterning Matthew McFarland – University of Nottingham, United Kingdom
	(P010) Co-translational folding of gamma-B crystallin within the ribosomal exit tunnel Linda Schulte – Goethe University Frankfurt, Germany
	(P012) Investigating the properties of translational arrest motifs; interactions between the nascent chain and the ribosome Hazel Bracken – University of Glasgow, United Kingdom
	(P014) Measuring Endoplasmic Reticulum Signals Sequence Translocation Efficiency Using the XBP1 Arrest Peptide Tara Hessa – Stockholm University, Sweden
	(P016) Co-translational folding of RnaseH Marija Liutkute – Max Planck Institute for Biophysical Chemistry, Germany

09:10 – 09:40	(S008) Interaction of the N-acetyl transferase NatA with the ribosome Martin Pool – University of Manchester, UK
09:40 – 10:10	(S009) Co-translational interactions of nascent chains revealed by ribosome profiling Bernd Bukau – University of Heidelberg, Germany
10:10 – 10:30	(OC003) Dual function of the ribosome and the trigger factor chaperone in nascent protein folding Christian Kaiser – Johns Hopkins University, United States

11:00 – 11:30	(S010) Real-Time Folding of Proteins Emerging From the Ribosome Marina Rodnina – Max Planck Institute for Biophysical Chemistry, Gottingen, Germany
11:30 – 12:00	(S011) Antibiotics and peptides in the ribosomal exit tunnel Alexander (Shura) Mankin – University of Illinois at Chicago, USA

	(S001) Menthol in Everyday Life: A Sensory Approach to Engaging Publics Andrew Balmer – University of Manchester, United Kingdom
	(OC005) Risk perception of synthetic biology: the role of cognitive biases Lauren Swiney – University of Warwick

13:00 – 13:30	(S002) METABOLIC ENGINEERING OF YEAST FOR PRODUCTION OF FUELS AND CHEMICALS Jens Nielsen – Chalmers University of Technology, Sweden
13:30 – 13:40	(OC008) Pushing the boundaries of protein design: modularity and automation Fabio Parmeggiani – University of Bristol, United Kingdom
13:40 – 13:55	(OC003) RISC-based logic Ali Ghareeb – Newcastle University, United Kingdom
13:55 – 14:05	(OC006) Smart Minimal Gene Sets using Whole Cell Models Joshua Rees – University of Bristol, United Kingdom
14:05 – 14:15	(OC018) Do we need to loosen the hold of the ELSI paradigm in synthetic biology? Kenneth Taylor – Peals Research Centre, Newcastle University, United Kingdom
14:15 – 14:40	(S003) Standard enabled workflows for design, build and test in synthetic biology Anil Wipat – Newcastle University

15:10 – 15:35	(S004) Synthetic Biology: A New Engine for the Third Wave of Biotechnology Huimin Zhao – University of Illinois at Urbana-Champaign, United States
15:35 – 15:45	(OC002) Construction of a library of synthetic DNA parts for metabolic optimisation in Cupriavidus necator using a Beckman Coulter robotic platform Magdalena Jonczyk – University of Nottingham, United Kingdom
15:45 – 15:55	(OC024) Neochromosomes – a synthetic biology way to answer biological questions Daniel Schindler – Manchester Institute of Biotechnology, United Kingdom
15:55 – 16:00	(OC021) Supporting SynBio through Efficient Tools Axel Trefzer – Thermo Fisher Scientific GENEART GmbH
16:00 – 16:10	(OC022) A systematic approach to design regulated synthetic promoters with tuneable outputs for plastic up-cycling in Pseudomonas putida KT2440 Manuel Salvador – University of Surrey, United Kingdom
16:10 – 16:20	(OC010) DualUTR – A novel 5′-untranslated region design for synthetic biology applications Rahmi Lale – Norwegian University of Science and Technology, Norway
16:20 – 16:25	(OC012) Design, build and validation of Isogenica’s fully synthetic human Fab library John Kendall – Isogenica, United Kingdom
16:25 – 16:35	(OC007) Identification and exploration of functional plasticity regions in plant monoterpene synthases for synthetic biology applications Nicole Leferink – SYNBIOCHEM, Manchester Institute of Biotechnology, United Kingdom
16:35 – 16:45	(OC014) miRNA-mediated regulation of synthetic gene circuits in the green alga Chlamydomonas reinhardtii Francisco J Navarro – UNIVERSITY OF CAMBRIDGE

	(S005) Reprogramming the Genetic Code Jason Chin – MRC Laboratory of Molecular Biology, United Kingdom
	(OC004) Synthetic Biology: Technologies towards Production of Living DNA Nanostructures in Cells Johann Elbaz – Tel Aviv University, Israel
	(OC013) Design Build Test Learn, Repeat: Collaborative Hardware Development for Synthetic Biology Harry Singer – Singer Instruments
	(OC009) Deep refactoring of central carbon metabolism in the soil bacterium Pseudomonas putida Alberto Sánchez-Pascuala – National Centre for Biotechnology (CNB), CSIC, Spain
	(S007) Mass Spectrometry Approaches for Synthetic Biology Analytics – How much do you want to know? Perdita Barran – University of Manchester, United Kingdom

	(S006) Coordination of Microbial Metabolism Uwe Sauer – ETH Zurich, Switzerland
	(OC001) Monitering of population dynamics of Escherichia coli Mutants during Long-Term Stationary Phase by the Bar-code deletion library. Hirotada Mori – Nara Institute of Science and Technology, Japan
	(OC017) Deinococcus geothermalis genome scale studies to engineer heterologous metabolic pathways Julie Zaworski – institute of Systems and Synthetic Biology, France
	(OC020) Yarrowia lipolytica as a synthetic biology chassis for the production of lipid-derived compounds Rodrigo Ledesma-Amaro – Imperial College London, United Kingdom

	(S009) Synthetic biology approaches to new chemistry Michelle Chang – University of California, United States
	(OC023) Streptomyces Cell-Free – Transcription, Translation and Biosynthesis Simon Moore – University of Kent, United Kingdom
	(OC011) Improvement of transformation and creation of synthetic pathways in the anaerobic whole cell biocatalyst Clostridium pasteurianum Alexander Grosse-Honebrink – University of Nottingham, United Kingdom
	(S008) Synthetic biology at Amyris: Industrial production of terpenes and more from milligrams to kilotonnes Chris Paddon – Amyris, Inc., United States
	(OC019) Growing programmable functional biomaterials with engineered kombucha-inspired co-cultures Charlie Gilbert – Imperial College London, United Kingdom
	(OC016) An automated Design/Build/Test/Learn pipeline for microbial fine chemical production. Adrian Jervis – University of Manchester, United Kingdom
	(OC015) Private and public values in emerging science and technology: an analysis of patents in synthetic biology Barbara Ribeiro – University of Manchester, United Kingdom
	(S010) Genetic control of mosquitoes Luke Alphey – The Pirbright Institute, United Kingdom

11:10 – 11:40	(S03) G-Quadruplexes: The DNA Quadruple Helix Sir Shankar Balasubramanian – University of Cambridge
11:40 – 12:10	(S11) DNA damage by carcinogens Francis L Martin – UCLan
12:10 – 12:40	(S08) Structural and Biochemical analyses of the archaeal HerA ATPase, NurA nuclease and the Mre11–Rad50 DNA repair complexes. Nick Robinson – Lancaster University

13:30 – 14:00	(S10) King Richard III: the resolution of a 500 year old cold case Dr Turi King – University of Leicester
14:00 – 14:30	(S04) DNA diversity in humans Mark Jobling – University of Leicester
14:30 – 14:45	(P04) Do we ‘see’ Hydrogen bonds in ultra-high-resolution scanning probe images of 2D Hydrogen-bonded molecular islands? Adam Sweetman – University of Nottingham

15:15 – 15:45	(S05) Hydrogen bonding and Ionic Liquids Patricia Hunt – Imperial College London
15:45 – 16:15	(S06) Hydrogen bonds in cellulose and cellulose derivatives – bone and bane Thomas Heinze – Friedrich Schiller University of Jena
16:15 – 16:45	(S07) DNA and fruit ripening Graham Seymour – Prof.

09:20 – 09:40	(S09) The 1947 Discovery by Creeth, Gulland and Jordan Stephen Harding – University of Nottingham
09:40 – 10:10	(S01) Modern Methods for Modelling DNA Structure and its Interactions Sarah Harris – University of Leeds
10:10 – 10:40	(S02) Chemical ligation of nucleic acids, biocompatibility of artificial DNA backbones, and potential applications Tom Brown – Oxford University

	(P02) Insulin self-interactions at clinical dosage concentrations Richard Gillis – University of Nottingham
	(P03) Structural investigation of the rhodopsin (Rho)-guanylyl cyclase (GC) protein from Blastocladiomycota. Hadeeqa Raza – University of Nottingham
	(P05) Exoelectrogenic Process Intensification of Aerobic C1 Gas Fermentation Vera Salgado – University of Nottingham
	(P06) Novel applications of hydrodynamic methods for the molecular characterisation of spent hop extracts Arthur Gadon – University of Nottingham
	(P07) Targeting tRNA-(N¹G37) methyltransferase (TrmD) for the discovery of novel antibacterials against intracellular pathogens Josh Prince – University of Southampton
	(P08) Hydrodynamics of the enterococcal VanA-type VanS membrane sensor kinase: first evidence for interactions with vancomycin Mary Phillips-Jones – University of Central Lancashire
	(P09) Interactions of DNA with the polycationic glycan chitosan Stephen Harding – University of Nottingham
	(P010) Hydrodynamic integrity of mucin and its non-covalent interactions with flavour compounds Vlad Dinu – University of Nottingham
	(P011) The dimerization of the antibiotic vancomycin is fully reversible – and weak Mary Phillips-Jones – University of Central Lancashire
	(P012) Phenyl Saligenin Phosphate Induced Neurodegeneration in Differentiating Mouse N2a cells Najiah Alyamani – Nottingham Trent University
	(P013) Towards safe and sustainable farming. Elucidating the role of the Major Outer Membrane Protein (MOMP) of Campylobacter jejuni within gut epithelia Jennifer Okoye – University of Nottingham
	(P014) Hydrodynamic investigation of interactions in polysaccharide-insulin complexes Shahwar Jiwani – University of Nottingham
	(P15) Microwave assisted template self-assembly for WO₃ nanoparticle synthesis Sharad Amin – University of Nottingham