The 1st Biochemical Society and Against Breast Cancer Glyco Oncology Workshop 2017
We aimed to share the latest technological advances, mechanistic understanding and knowledge in the field of onco-glycobiology and to foster communication and collaboration to expedite research for earlier diagnosis, better monitoring and treatments for cancer patients, with a focus on metastatic breast cancer.
Glycobiology is a dynamic, rapidly evolving research field. Researchers are often geographically dispersed and have historically benefited from strong interdisciplinary collaboration. Recent developments in analytical methods and mechanistic understanding make it timely to converge researchers already active in the field, those from other disciplines and technology development experts to advance research and develop novel diagnostic tools and treatments, particularly for metastatic cancer patients. The workshop consisted of short (flash) presentations followed by round table discussions on ‘hot topics’, training sessions targeted to new technologies and ‘surgeries’ to link up established glycobiology experts with groups needing support and specific techniques. |
Organizers:
Cathy Merry (University of Nottingham)
Nicola Winstone (Against Breast Cancer)
Thursday 6 April 2017
08:30 – 09:00 Registration
09:00 – 09:20 Introduction: glycosylation in cancer
09:20 – 09:30
Role of heparanase in establishing a microenvironment that supports tumor growth and metastasis
Ralph Sanderson (University of Alabama at Birmingham, U.S.A.)
09:30 – 09:40
High sensitivity glycomics: biomarkers and glycan “shields”
Anne Dell (Imperial College London, United Kingdom)
09:40 – 09:50
Aberrant O-linked glycosylation in breast cancer results in modulation of the immune micro-environment.
Joy Burchell (King’s College London, United Kingdom)
09:50 – 10:00
Hyaluronan and cancer
Vera Gorbunova (University of Rochester, U.S.A.)
10:00 – 10:45 Flash presentations
10:45 – 11:15 Refreshment Break
11:15 – 12:30 First round table discussion session
Break into sessions based on the topics discussed above
12:30 – 13:30 Lunch
13:30 – 14:30 Second round table discussion session
Opportunity to move to a new topic discussion
14:30 – 15:30 Third round table discussion session
Opportunity to move to a new topic discussion
15:30 – 16:00 Refreshment Break
16:00 – 17:00 Open discussion to identify the ‘known unknowns’ in onco-glycobiology
17:00 – 17:30 Summary and closing comments
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