Lipidation in cell biology and disease
Abstract deadline: 3 August 2021 Fatty acylation has emerged as an exciting, dynamic protein modification that controls many aspects of protein function, including membrane trafficking and targeting, protein-protein interactions and enzymic activity. Our understanding of the myriad of pathways that are regulated by these lipid modifications has drastically increased and has led to an abundance of new targets for therapies to treat diseases including many cancers, infections, and neurodegeneration. The structures for several enzymes that regulate fatty acylation have been identified recently, aiding the “druggability” of these targets for therapeutic gain as well as parsing apart their roles in cell biology. This online meeting will provide a forum for the discussion of new discoveries in the field of fatty acylation.