Hydrogen Bonds & DNA: Commemoration of the 70th anniversary of the discovery by JM Creeth and colleagues at Nottingham in 1947

Name: Hydrogen Bonds & DNA: Commemoration of the 70th anniversary of the discovery by JM Creeth and colleagues at Nottingham in 1947
Start: 2017-11-10
End: 2017-11-10

A Biochemical Society and RSC Chemistry Biology Interface Division Focused Meeting

This one-day meeting was held to mark the 70th anniversary of the publication in the Journal of the Chemical Society, of the discovery of hydrogen bonds in DNA, but also offered insight into the latest techniques and discoveries around the area.

Discovered by PhD student J. Michael Creeth, under the supervision of Dr D.O Jordan and Professor J.M Gulland FRS at (the then) University College Nottingham, the discovery paved the way for the double helix model by Watson and Crick 6 years later.

Stephen Harding, Dr Creeth’s last Post-doctoral Research Assistant at the University of Bristol, led the commemoration with a brief history of the discovery in 1947 before several esteemed speakers brought us up-to-date with the latest research and findings around both Hydrogen Bonds and DNA.

Following the lecture we unveiled a commemorative plaque on the site of the former Nucleic Acid Laboratory in the University of Nottingham’s Trent Building, by the Vice Chancellor and the Creeth family.

09:15 – 09:20 Welcome- Professor Sir Martyn Poliakoff FRS

Session one

09:20 – 09:40	(S09) The 1947 Discovery by Creeth, Gulland and Jordan Stephen Harding – University of Nottingham
09:40 – 10:10	(S01) Modern Methods for Modelling DNA Structure and its Interactions Sarah Harris – University of Leeds
10:10 – 10:40	(S02) Chemical ligation of nucleic acids, biocompatibility of artificial DNA backbones, and potential applications Tom Brown – Oxford University

Session two

11:10 – 11:40	(S03) G-Quadruplexes: The DNA Quadruple Helix Sir Shankar Balasubramanian – University of Cambridge
11:40 – 12:10	(S11) DNA damage by carcinogens Francis L Martin – UCLan
12:10 – 12:40	(S08) Structural and Biochemical analyses of the archaeal HerA ATPase, NurA nuclease and the Mre11–Rad50 DNA repair complexes. Nick Robinson – Lancaster University

Lunch and Poster session

	(P02) Insulin self-interactions at clinical dosage concentrations Richard Gillis – University of Nottingham
	(P03) Structural investigation of the rhodopsin (Rho)-guanylyl cyclase (GC) protein from Blastocladiomycota. Hadeeqa Raza – University of Nottingham
	(P05) Exoelectrogenic Process Intensification of Aerobic C1 Gas Fermentation Vera Salgado – University of Nottingham
	(P06) Novel applications of hydrodynamic methods for the molecular characterisation of spent hop extracts Arthur Gadon – University of Nottingham
	(P07) Targeting tRNA-(N¹G37) methyltransferase (TrmD) for the discovery of novel antibacterials against intracellular pathogens Josh Prince – University of Southampton
	(P08) Hydrodynamics of the enterococcal VanA-type VanS membrane sensor kinase: first evidence for interactions with vancomycin Mary Phillips-Jones – University of Central Lancashire
	(P09) Interactions of DNA with the polycationic glycan chitosan Stephen Harding – University of Nottingham
	(P010) Hydrodynamic integrity of mucin and its non-covalent interactions with flavour compounds Vlad Dinu – University of Nottingham
	(P011) The dimerization of the antibiotic vancomycin is fully reversible – and weak Mary Phillips-Jones – University of Central Lancashire
	(P012) Phenyl Saligenin Phosphate Induced Neurodegeneration in Differentiating Mouse N2a cells Najiah Alyamani – Nottingham Trent University
	(P013) Towards safe and sustainable farming. Elucidating the role of the Major Outer Membrane Protein (MOMP) of Campylobacter jejuni within gut epithelia Jennifer Okoye – University of Nottingham
	(P014) Hydrodynamic investigation of interactions in polysaccharide-insulin complexes Shahwar Jiwani – University of Nottingham
	(P15) Microwave assisted template self-assembly for WO₃ nanoparticle synthesis Sharad Amin – University of Nottingham

Session three

13:30 – 14:00	(S10) King Richard III: the resolution of a 500 year old cold case Dr Turi King – University of Leicester
14:00 – 14:30	(S04) DNA diversity in humans Mark Jobling – University of Leicester
14:30 – 14:45	(P04) Do we ‘see’ Hydrogen bonds in ultra-high-resolution scanning probe images of 2D Hydrogen-bonded molecular islands? Adam Sweetman – University of Nottingham

Session four

15:15 – 15:45	(S05) Hydrogen bonding and Ionic Liquids Patricia Hunt – Imperial College London
15:45 – 16:15	(S06) Hydrogen bonds in cellulose and cellulose derivatives – bone and bane Thomas Heinze – Friedrich Schiller University of Jena
16:15 – 16:45	(S07) DNA and fruit ripening Graham Seymour – Prof.

Final Session

16:45 – 17:00 Poster Prize and Closing Remarks Prof Steve Harding (NCMH, UK)
17:00 Plaque unveiling by the Creeth family

Date

Nov 10 2017

Time

All Day