Monday 11 December

12:30 – 13:15 – Registration and Lunch
13:15 – 15:10 – Session one
13:30 – 14:00 (S001) Silent polymorphic mutations (sSNP) speak out: alterations of protein function and folding by sSNPs
Zoya Ignatova – Universitat Hamburg, Germany
14:00 – 14:30 Translation Rate and Protein Fate
Patricia Clark – University of Notre Dame, USA
14:30 – 14:50 (OC006) The ribosome restrains molten globule formation in stalled nascent flavodoxin
Carlo van Mierlo – Laboratory of Biochemistry; Wageningen University, Netherlands
14:50 – 15:10 (OC004) Kinetic and structural comparison of the co-translational and refolding pathways of HaloTag
Avi Samelson – University of California, San Francisco, United States
15:10 – 15:40 – Refreshment break
15:40 – 17:00 – Session two
15:40 – 16:10 (S002) Co-translational folding of alpha helical membrane proteins in lipid bilayers
Paula Booth – Kings College London, UK
16:10 – 16:30 (OC002) Disulfide formation during nascent polypeptide folding
Philip Robinson – University of Glasgow, United Kingdom
17:00 – 18:00 – Poster session 1
(P001) The Endoplasmic Reticulum Membrane Protein Complex (EMC) cooperates with the Sec61 translocon to enable the biogenesis of polytopic membrane proteins
Matthew Shurtleff – University of California, San Francisco
(P003) Isolation of RNCs as a strategy to characterise ribosomal heterogeneity in M. tuberculosis
Beth Sawyer – London School of Hygiene & Tropical Medicine, United Kingdom
(P005) Translational Termination Factors catalyse the Release of the Nascent Chain on a Proline Codon in the 2A- coding mRNA
Man Balola – Mosul University, United Kingdom
(P007) The ribosome modulates cotranslational folding depending on protein size and net charge
Jose Arcadio Farias Rico – Stockholm University, Sweden
(P009) NMR measurements of dynamics and protein-ribosome interactions in ribosome–nascent chain complexes
Christopher Waudby – University College London, United Kingdom
(P011) The mechanism of cotranslational recognition of nascent substrate proteins by the translocation ATPase SecA
Damon Huber – University of Birmingham, United Kingdom
(P013) Assembly in the translation milieu imposes evolutionary constraints on homomeric proteins
Eviatar Natan – The Aleph Lab
(P015) Insights into Ribosome Force Profile Assays: Releasing the Stall
Carolina Mendonca – University of Cambridge, United Kingdom

Tuesday 12 December

09:30 – 11:00 – Session three
09:30 – 10:00 (S003) Structural and mechanistic insight into nascent-polypeptide mediated translational stalling
Daniel Wilson – University of Hamburg, Germany
10:00 – 10:30 Structures of Prokaryotic and Eukaryotic Ribosomal Complexes Involved in Initiation, Maturation and Targeting of Proteins to Membranes
Nenad Ban – ETH Zurich, Switzerland
10:30 – 10:50 (OC005) Origins of the Mechanochemical Coupling of Peptide Bond Formation and Protein Synthesis
Edward O’Brien – Penn State University, USA
11:00 – 11:30 – Refreshment break
11:30 – 13:00 – Session four
11:30 – 12:00 (S004) Cotranslational protein folding
Gunnar von Heijne – Stockholm University, Sweden
12:00 – 12:30 Principles of Protein Structural Ensemble Determination
Michele Vendruscolo – University of Cambridge, UK
12:30 – 13:00 Kinetics of peptide and protein aggregation
Alexander Buell – University of Düsseldorf, Germany
13:00 – 14:00 – Lunch
14:00 – 15:20 – Session five
14:00 – 14:30 (S005) Regulation of Human Translation Termination by Factors bound to the mRNA 3’Untranslated Region
Christiane Berger-Schaffitzel – University of Bristol, United Kingdom
14:30 – 15:00 (S006) Structural studies of protein folding on the ribosome
Lisa Cabrita – University College London, United Kingdom
15:00 – 15:20 (OC001) The translating human mitochondrial ribosome in action – snapshots observed by cryo-EM
Shintaro Aibara – Science for Life Laboratory / Stockholm University, Sweden
15:30 – 16:00 – Refreshment Break
16:00 – 17:00 – Keynote Speaker
16:00 – 17:00 (S007) The exit tunnel in mitochondrial ribosomes
Venki Ramakrishnan – LMB Cambridge, UK
17:00 – 18:00 – Poster session 2
(P002) Investigating the insertion and folding of alpha helical membrane proteins into lipid bilayers using a cell free expression system
Nicola Harris – King’s College London, United Kingdom
(P004) Elongation Nascent Peptides in All-Atom Molecular Dynamics Simulations
Michal H. Kolar – Max Planck Institute for Biophysical Chemistry, Germany
(P006) Developing cell-free expression for studies of co-translational membrane protein folding
Grant Pellowe – King’s College London, United Kingdom
(P008) A component of the ribosome exit tunnel is required for Hox gene translation during Drosophila embryonic patterning
Matthew McFarland – University of Nottingham, United Kingdom
(P010) Co-translational folding of gamma-B crystallin within the ribosomal exit tunnel
Linda Schulte – Goethe University Frankfurt, Germany
(P012) Investigating the properties of translational arrest motifs; interactions between the nascent chain and the ribosome
Hazel Bracken – University of Glasgow, United Kingdom
(P014) Measuring Endoplasmic Reticulum Signals Sequence Translocation Efficiency Using the XBP1 Arrest Peptide
Tara Hessa – Stockholm University, Sweden
(P016) Co-translational folding of RnaseH
Marija Liutkute – Max Planck Institute for Biophysical Chemistry, Germany
19:30 – 21:00 – Conference dinner

Wednesday 13 December

09:10 – 10:30 – Session six
09:10 – 09:40 (S008) Interaction of the N-acetyl transferase NatA with the ribosome
Martin Pool – University of Manchester, UK
09:40 – 10:10 (S009) Co-translational interactions of nascent chains revealed by ribosome profiling
Bernd Bukau – University of Heidelberg, Germany
10:10 – 10:30 (OC003) Dual function of the ribosome and the trigger factor chaperone in nascent protein folding
Christian Kaiser – Johns Hopkins University, United States
10:30 – 11:00 – Refreshment Break
11:00 – 12:00 – Session seven
11:00 – 11:30 (S010)  Real-Time Folding of Proteins Emerging From the Ribosome
Marina Rodnina – Max Planck Institute for Biophysical Chemistry, Gottingen, Germany
11:30 – 12:00 (S011) Antibiotics and peptides in the ribosomal exit tunnel
Alexander (Shura) Mankin – University of Illinois at Chicago, USA
12:00  – Concluding remarks and meeting close