Molecule of the Month
May 2024

CFTR and Cystic Fibrosis

Cystic fibrosis is currently treated using drugs that enhance the function of mutated CFTR

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PDB data help explain fundamental biology, biomedicine, bioengineering/biotechnology, and energy sciences
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Use PDB-101 resources to learn about the structural biology of athletics and well-being
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SciArt Galleries
Irving Geis (1908-1997) was a gifted artist who helped illuminate the field of structural biology with his iconic images. The Geis Digital Archive features many of his illustrations in the context of their molecular structures.

Images used with permission from the Howard Hughes Medical Institute (www.hhmi.org). All rights reserved.

Intermolecular Contacts in Hemoglobin S

Hemoglobin S

DPG-Hemoglobin Complex

Z-DNA

Cytochrome c (unbound)

Carboxypeptidase A

Deoxyribonucleic Acid (DNA)

Trypsin

Induced Lac Repressor

Myoglobin

Hemoglobin (1000)

Myoglobin Fold

Ribonuclease S

DNA

Aspartate Transcarbamoylase (ATCase)

Collagen

Oxyhemoglobin

A-DNA

Crambin

Hemoglobin

Cytochrome c

TATA-Binding Protein (TBP)

Immunoglobulin G (IgG)

Lac Repressor

Deoxyhemoglobin

Myohemerythrin

Lysozyme (488)

Lysozyme (512)

Transfer Ribonucleic Acid (tRNA)

B-DNA

Tomato Bushy Stunt Virus (TBSV)

The Molecular Landscapes by David S. Goodsell integrate information from structural biology, microscopy and biophysics to simulate detailed views of the molecular structure of living cells.

Illustrations are free for use under a CC-BY-4.0 license

Biosites: Nucleus

Vascular Endothelial Growth Factor (VegF) Signaling

Biosites: Basement Membrane

Insulin Release

Caulobacter Polar Microdomain

Casein Micelle and Fat Globule in Milk

Chloroplast

Myoglobin in a Whale Muscle Cell

HIV-Infected Cell

Coronavirus Life Cycle

HIV Vaccine

Abiogenesis

Biosites: Red Blood Cell

Respiratory Droplet

SARS-CoV-2 Fusion

Biosites: Blood Plasma

HIV in Blood Plasma

Biosites: Muscle

Phage-based COVID-19 Vaccine

SARS-CoV-2 and Neutralizing Antibodies

Excitatory and Inhibitory Synapses

SARS-CoV-2 mRNA Vaccine

Autophagy

Influenza Vaccine

Biosites: Cytoplasm

Blood

Ebola Virus

Poliovirus Neutralization

Coronavirus

Last Universal Common Ancestor

Escherichia coli

Mycoplasma mycoides

Red Blood Cell Cytoskeleton

Escherichia coli Bacterium

Zika Virus

Collagen and Extracellular Matrix

Transfer RNA and Gag Protein

Model of a Mycoplasma Cell

RecA and DNA

Immunological Synapse

Bacteriophage T4 Infection

Insulin Action

JCVI-syn3A Minimal Cell

CytoSkeleton

Cellulose Synthase

Myelin

Lipid Droplets

Measles Virus Proteins